HORIBA SZ-100V2 Nanoparticle Analyzer
Dynamic Light Scattering (DLS) Technology | Three in One Particle Size, Zeta Potential, and Molecular Weight | ppm to 40% Concentration | Trace Sample 12 μ L
0.3nm~10μm
Particle size measurement range
-500~+500mV
Zeta potential range
1x103~2x107 Da
Molecular weight measurement range
ninety°;+173°;
Dual angle measurement
SZ-100V2 It is a compact and powerful nanoparticle characterization system that integrates one machineDynamic Light Scattering (DLS) Particle Size Measurement, Zeta Potential Analysis, and Molecular Weight DeterminationThree major functions. Unique dual light path design (ninety°; and 173°Covering from ppm level dilute solution to 40% high concentration slurry, only 12 μ L of trace sample is needed for machine operation, and conventional measurement only takes 2 minutes. Widely used in the fields of biopharmaceuticals, nanomaterials, coatings and inks, chemicals, and energy.
五大核心优势
three
Three parameters of one instrument
Synchronize the measurement of particle size, Zeta potential, and molecular weight (Mw/A2) without the need for hardware replacement, greatly improving the efficiency of research and quality inspection.
Wide Field
Ultra wide concentration coverage
From ppm protein to 40% high concentration slurry, it can be directly measured with almost no dilution, suitable for various actual sample states.
trace
Micro sample adaptation
Specially designed for precious samples, with a minimum requirement of only 12 μ L, compatible with disposable, semi micro, glass, and flow cells to meet diverse needs.
Double angle
Dual light path and dual angle
90°; and 173°Dual detection angles, automatic optimization of signal-to-noise ratio, accurate characterization of wide distribution and multi dispersion systems.
anti-fouling
Design for preventing cross contamination
Disposable Zeta potential sample cell eliminates cross contamination between samples; Specialized graphite electrodes can be used to measure high salt and highly corrosive samples.
Three major measurement principles
Dynamic Light Scattering (DLS) - Particle SizeAnalyze the relationship between the fluctuation speed and particle size caused by the Brownian motion of nanoparticles, covering from 0.3nm to 10 μ m.
Laser Doppler Electrophoresis Zeta PotentialApply an electric field to move charged particles, measure the Doppler shift of scattered light, obtain Zeta potential (-500~+500mV), and evaluate the stability of the dispersion system.
Static light scattering - molecular weightUsing the Debye point method, measure the scattered light intensity at different concentrations and calculate the absolute molecular weight (Mw) and second virility coefficient (A2).
典型应用领域
biopharmaceuticalnanomaterialsPaint InkSemiconductor CMP slurryBatteries and Energy MaterialsCosmetics and Personal CareFood and BeverageAcademic and Research
Flexible attachment options
Sample pool options
| Disposable sample pool | Economy, no cross contamination |
| Semi micro/micro tank | Only 100 μ L or 12 μ L is needed |
| Glass pool/flow pool | Reusable or online connection |
| Zeta potential plastic/glass cell | Compatible with both aqueous and organic phases |
upgrade module
| Automatic titrator | pH、 Automatic titration of concentration, determination of isoelectric point |
| graphite electrode | Corrosion resistant and high salt samples |
| Micro sample pool kit | 12 μ L ultra micro measurement |
产品参数
| 测量原理 | Particle size: Dynamic Light Scattering (DLS) method; Zeta potential: laser Doppler electrophoresis method; Molecular weight: Debye point method (static light scattering) |
| Particle size measurement range | 0.3 nm - 10 μm | Zeta potential range | -500 mV - +500 mV |
| Molecular weight range (Debye) | 1,000 - 2x10^7 Da | Molecular weight range (MHS) | 540 - 2x10^7 Da |
| Maximum sample concentration | 40 wt% | measure angle | 90 degrees and 173 degrees |
| Sample pool type | Disposable, semi trace, trace, glass, flow cell, Zeta potential dedicated cell | Automatic titrator | Optional (pH/concentration titration) |
| Minimum sample size | 12 μL | Typical measurement time | About 2 minutes |
Typical Measurement Cases
Biomaterials: Measurement of colloidal gold particle size (NIST standard substance)
| NIST standard substance | RM8011 (10nm) | RM8012 (30nm) | RM8013 (60nm) |
|---|
| NIST reference value (nm) | thirteen point five | twenty-six point five | fifty-five point three |
| SZ-100V2 measurement value (nm) | eleven | twenty-six point six | fifty-five point four |
Frequently Asked Questions
Can SZ-100V2 measure high concentration samples? Do you need dilution?
Okay. The design of SZ-100V2 allows for direct measurement of samples up to 40 wt% without the need for dilution. The unique 173 degree backscattered optical path is particularly suitable for high concentration and turbid samples, avoiding interference from multiple scattering. For low concentration samples such as proteins, a 90 degree optical path provides higher sensitivity. Dual light path automatic optimization, covering the full range from ppm level to high concentration.
What is the practical significance of Zeta potential measurement?
Zeta potential is a key parameter for measuring the stability of dispersed systems. Usually, a Zeta potential absolute value greater than 30mV indicates system stability, while a value below 20mV is prone to agglomeration or settling. By adjusting pH, ionic strength, or adding surfactants, the Zeta potential can be optimized to achieve long-term stable dispersion in product development such as coatings, inks, and ceramic slurries.
Does molecular weight measurement require additional attachments?
No need. SZ-100V2 directly measures absolute molecular weight (Mw) and second virility coefficient (A2) through static light scattering (Debye point method). It comes standard with a standard sample cell and a range of concentration samples. Molecular weight can also be estimated from DLS particle size using the Mark Houwink equation.
How to handle strong acid, strong alkali or high salt samples?
HORIBA provides dedicated graphite electrodes and corrosion-resistant Zeta potential sample cells, specifically designed for measuring samples in harsh environments such as high salt, strong acid, and strong alkali. At the same time, disposable sample tanks can effectively avoid cross contamination.
Is the equipment operation complicated? Do you need specialized training?
SZ-100V2 is equipped with intelligent software that automatically optimizes measurement parameters and data analysis. The simple guided operation process enables new users to quickly get started. Simultaneously provide comprehensive training materials and application support.
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查看详情 →Free sample testing service
Free Sample Testing Service
Not sure if your nanoparticles or suspension are suitable for SZ-100V2 analysis? We offer free sample testing services! Send us samples, and professional engineers will conduct particle size, Zeta potential, or molecular weight tests and provide detailed reports.
